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2fp1

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==Secreted Chorismate Mutase from Mycobacterium tuberculosis==
==Secreted Chorismate Mutase from Mycobacterium tuberculosis==
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<StructureSection load='2fp1' size='340' side='right' caption='[[2fp1]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
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<StructureSection load='2fp1' size='340' side='right'caption='[[2fp1]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2fp1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FP1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FP1 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2fp1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FP1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FP1 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PB:LEAD+(II)+ION'>PB</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2fp2|2fp2]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PB:LEAD+(II)+ION'>PB</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chorismate_mutase Chorismate mutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.5 5.4.99.5] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fp1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fp1 OCA], [https://pdbe.org/2fp1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fp1 RCSB], [https://www.ebi.ac.uk/pdbsum/2fp1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fp1 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fp1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fp1 OCA], [http://pdbe.org/2fp1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2fp1 RCSB], [http://www.ebi.ac.uk/pdbsum/2fp1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2fp1 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SCMU_MYCTO SCMU_MYCTO]] Catalyzes the Claisen rearrangement of chorismate to prephenate. May play some role in the pathogenicity (By similarity).
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[https://www.uniprot.org/uniprot/SCMU_MYCTU SCMU_MYCTU] Catalyzes the Claisen rearrangement of chorismate to prephenate. May play some role in the pathogenicity.<ref>PMID:15654876</ref> <ref>PMID:15737998</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fp/2fp1_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fp/2fp1_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</div>
</div>
<div class="pdbe-citations 2fp1" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2fp1" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[3D structures of chorismate mutase|3D structures of chorismate mutase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Chorismate mutase]]
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[[Category: Large Structures]]
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[[Category: Dey, R]]
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Grahn, E]]
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[[Category: Dey R]]
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[[Category: Kast, P]]
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[[Category: Grahn E]]
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[[Category: Krengel, U]]
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[[Category: Kast P]]
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[[Category: Okvist, M]]
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[[Category: Krengel U]]
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[[Category: Sasso, S]]
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[[Category: Okvist M]]
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[[Category: Alpha-helical]]
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[[Category: Sasso S]]
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[[Category: Isomerase]]
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Current revision

Secreted Chorismate Mutase from Mycobacterium tuberculosis

PDB ID 2fp1

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