This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2jbz

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (06:41, 1 May 2024) (edit) (undo)
 
(13 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2jbz.gif|left|200px]]
 
-
{{Structure
+
==Crystal structure of the Streptomyces coelicolor holo-[Acyl-carrier-protein] Synthase (AcpS) in complex with coenzyme A at 1.6 A==
-
|PDB= 2jbz |SIZE=350|CAPTION= <scene name='initialview01'>2jbz</scene>, resolution 1.62&Aring;
+
<StructureSection load='2jbz' size='340' side='right'caption='[[2jbz]], [[Resolution|resolution]] 1.62&Aring;' scene=''>
-
|SITE= <scene name='pdbsite=AC1:Coa+Binding+Site+For+Chain+A'>AC1</scene>
+
== Structural highlights ==
-
|LIGAND= <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>
+
<table><tr><td colspan='2'>[[2jbz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_coelicolor Streptomyces coelicolor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JBZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JBZ FirstGlance]. <br>
-
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Holo-[acyl-carrier-protein]_synthase Holo-[acyl-carrier-protein] synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.8.7 2.7.8.7] </span>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.62&#8491;</td></tr>
-
|GENE=
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-
|DOMAIN=
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jbz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jbz OCA], [https://pdbe.org/2jbz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jbz RCSB], [https://www.ebi.ac.uk/pdbsum/2jbz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jbz ProSAT]</span></td></tr>
-
|RELATEDENTRY=
+
</table>
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jbz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jbz OCA], [http://www.ebi.ac.uk/pdbsum/2jbz PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2jbz RCSB]</span>
+
== Function ==
-
}}
+
[https://www.uniprot.org/uniprot/ACPS_STRCO ACPS_STRCO] Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.[HAMAP-Rule:MF_00101]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jb/2jbz_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jbz ConSurf].
 +
<div style="clear:both"></div>
-
'''CRYSTAL STRUCTURE OF THE STREPTOMYCES COELICOLOR HOLO-[ACYL-CARRIER-PROTEIN] SYNTHASE (ACPS) IN COMPLEX WITH COENZYME A AT 1.6 A'''
+
==See Also==
-
 
+
*[[Acyl carrier protein synthase 3D structures|Acyl carrier protein synthase 3D structures]]
-
 
+
__TOC__
-
==About this Structure==
+
</StructureSection>
-
2JBZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_coelicolor Streptomyces coelicolor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JBZ OCA].
+
[[Category: Large Structures]]
-
[[Category: Holo-[acyl-carrier-protein] synthase]]
+
-
[[Category: Single protein]]
+
[[Category: Streptomyces coelicolor]]
[[Category: Streptomyces coelicolor]]
-
[[Category: Aglio, P Dall.]]
+
[[Category: Arthur C]]
-
[[Category: Arthur, C.]]
+
[[Category: Crosby J]]
-
[[Category: Crosby, J.]]
+
[[Category: Crump MP]]
-
[[Category: Crump, M P.]]
+
[[Category: Dall'Aglio P]]
-
[[Category: Hadfield, A T.]]
+
[[Category: Hadfield AT]]
-
[[Category: Law, C K.E.]]
+
[[Category: Law CKE]]
-
[[Category: acp]]
+
-
[[Category: acyl carrier protein synthase]]
+
-
[[Category: coenzyme some]]
+
-
[[Category: fatty acid biosynthesis]]
+
-
[[Category: lipid synthesis]]
+
-
[[Category: magnesium]]
+
-
[[Category: metal-binding]]
+
-
[[Category: phosphopantetheine arm]]
+
-
[[Category: poliketide]]
+
-
[[Category: transferase]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:55:56 2008''
+

Current revision

Crystal structure of the Streptomyces coelicolor holo-[Acyl-carrier-protein] Synthase (AcpS) in complex with coenzyme A at 1.6 A

PDB ID 2jbz

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools