2eqo

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==Solution structure of the stn_TRAF3IP1_nd domain of interleukin 13 receptor alpha 1-binding protein-1 [Homo sapiens]==
==Solution structure of the stn_TRAF3IP1_nd domain of interleukin 13 receptor alpha 1-binding protein-1 [Homo sapiens]==
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<StructureSection load='2eqo' size='340' side='right' caption='[[2eqo]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2eqo' size='340' side='right'caption='[[2eqo]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2eqo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EQO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EQO FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2eqo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EQO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EQO FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2eqo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eqo OCA], [http://pdbe.org/2eqo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2eqo RCSB], [http://www.ebi.ac.uk/pdbsum/2eqo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2eqo ProSAT], [http://www.topsan.org/Proteins/RSGI/2eqo TOPSAN]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2eqo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eqo OCA], [https://pdbe.org/2eqo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2eqo RCSB], [https://www.ebi.ac.uk/pdbsum/2eqo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2eqo ProSAT], [https://www.topsan.org/Proteins/RSGI/2eqo TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MIPT3_HUMAN MIPT3_HUMAN]] Plays an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules.<ref>PMID:10791955</ref> <ref>PMID:12935900</ref> <ref>PMID:12812986</ref>
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[https://www.uniprot.org/uniprot/MIPT3_HUMAN MIPT3_HUMAN] Plays an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules.<ref>PMID:10791955</ref> <ref>PMID:12935900</ref> <ref>PMID:12812986</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Dang, W]]
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[[Category: Large Structures]]
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[[Category: Inoue, M]]
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[[Category: Dang W]]
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[[Category: Kigawa, T]]
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[[Category: Inoue M]]
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[[Category: Muto, Y]]
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[[Category: Kigawa T]]
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[[Category: Structural genomic]]
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[[Category: Muto Y]]
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[[Category: Shirouzu, M]]
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[[Category: Shirouzu M]]
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[[Category: Terada, T]]
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[[Category: Terada T]]
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[[Category: Yokoyama, S]]
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[[Category: Yokoyama S]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Rsgi]]
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[[Category: Stn_traf3ip1_nd domain]]
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[[Category: Transcription]]
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Current revision

Solution structure of the stn_TRAF3IP1_nd domain of interleukin 13 receptor alpha 1-binding protein-1 [Homo sapiens]

PDB ID 2eqo

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