2ffh

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==THE SIGNAL SEQUENCE BINDING PROTEIN FFH FROM THERMUS AQUATICUS==
==THE SIGNAL SEQUENCE BINDING PROTEIN FFH FROM THERMUS AQUATICUS==
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<StructureSection load='2ffh' size='340' side='right' caption='[[2ffh]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
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<StructureSection load='2ffh' size='340' side='right'caption='[[2ffh]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2ffh]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_25104 Atcc 25104]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FFH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FFH FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2ffh]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_aquaticus Thermus aquaticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FFH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FFH FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ffh|1ffh]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ffh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ffh OCA], [http://pdbe.org/2ffh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ffh RCSB], [http://www.ebi.ac.uk/pdbsum/2ffh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ffh ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ffh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ffh OCA], [https://pdbe.org/2ffh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ffh RCSB], [https://www.ebi.ac.uk/pdbsum/2ffh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ffh ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SRP54_THEAQ SRP54_THEAQ]] Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY (By similarity).[HAMAP-Rule:MF_00306]
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[https://www.uniprot.org/uniprot/SRP54_THEAQ SRP54_THEAQ] Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY (By similarity).[HAMAP-Rule:MF_00306]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 25104]]
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[[Category: Large Structures]]
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[[Category: Freymann, D M]]
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[[Category: Thermus aquaticus]]
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[[Category: Keenan, R J]]
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[[Category: Freymann DM]]
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[[Category: Stroud, R M]]
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[[Category: Keenan RJ]]
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[[Category: Walter, P]]
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[[Category: Stroud RM]]
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[[Category: Ffh]]
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[[Category: Walter P]]
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[[Category: Gtpase]]
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[[Category: Helix-turn-helix]]
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[[Category: M domain]]
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[[Category: Protein targeting]]
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[[Category: Protein transport]]
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[[Category: Rna-binding]]
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[[Category: Signal recognition particle]]
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[[Category: Signal sequence-binding]]
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[[Category: Srp54]]
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Current revision

THE SIGNAL SEQUENCE BINDING PROTEIN FFH FROM THERMUS AQUATICUS

PDB ID 2ffh

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