6drv
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 6drv is ON HOLD Authors: Cianfrocco, M.A., Lahiri, I., DiMaio, F., Leschziner, A.E. Description: Beta-galactosidase [[Category: Unreleased Structur...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Beta-galactosidase== | |
| + | <SX load='6drv' size='340' side='right' viewer='molstar' caption='[[6drv]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6drv]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DRV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6DRV FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.2Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6drv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6drv OCA], [https://pdbe.org/6drv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6drv RCSB], [https://www.ebi.ac.uk/pdbsum/6drv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6drv ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/BGAL_ECOLI BGAL_ECOLI] | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Access to streamlined computational resources remains a significant bottleneck for new users of cryo-electron microscopy (cryo-EM). To address this, we have developed tools that will submit cryo-EM analysis routines and atomic model building jobs directly to Amazon Web Services (AWS) from a local computer or laptop. These new software tools ("cryoem-cloud-tools") have incorporated optimal data movement, security, and cost-saving strategies, giving novice users access to complex cryo-EM data processing pipelines. Integrating these tools into the RELION processing pipeline and graphical user interface we determined a 2.2A structure of ss-galactosidase in approximately 55h on AWS. We implemented a similar strategy to submit Rosetta atomic model building and refinement to AWS. These software tools dramatically reduce the barrier for entry of new users to cloud computing for cryo-EM and are freely available at cryoem-tools.cloud. | ||
| - | + | cryoem-cloud-tools: A software platform to deploy and manage cryo-EM jobs in the cloud.,Cianfrocco MA, Lahiri I, DiMaio F, Leschziner AE J Struct Biol. 2018 Jun 1. pii: S1047-8477(18)30138-2. doi:, 10.1016/j.jsb.2018.05.014. PMID:29864529<ref>PMID:29864529</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | [[Category: | + | </div> |
| - | [[Category: | + | <div class="pdbe-citations 6drv" style="background-color:#fffaf0;"></div> |
| - | [[Category: | + | |
| - | [[Category: Lahiri | + | ==See Also== |
| - | [[Category: | + | *[[Galactosidase 3D structures|Galactosidase 3D structures]] |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </SX> | ||
| + | [[Category: Escherichia coli K-12]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Cianfrocco MA]] | ||
| + | [[Category: DiMaio F]] | ||
| + | [[Category: Lahiri I]] | ||
| + | [[Category: Leschziner AE]] | ||
Current revision
Beta-galactosidase
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