6ds8
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of MhuD R26S mutant with two Manganese protoporphyrin IX bound per active site== | |
| + | <StructureSection load='6ds8' size='340' side='right'caption='[[6ds8]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6ds8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DS8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6DS8 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MNH:MANGANESE+PROTOPORPHYRIN+IX'>MNH</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ds8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ds8 OCA], [https://pdbe.org/6ds8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ds8 RCSB], [https://www.ebi.ac.uk/pdbsum/6ds8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ds8 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MHUD_MYCTU MHUD_MYCTU] Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron. | ||
| - | + | ==See Also== | |
| - | + | *[[Monooxygenase 3D structures|Monooxygenase 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mycobacterium tuberculosis H37Rv]] | ||
| + | [[Category: Chao A]] | ||
| + | [[Category: Goulding CW]] | ||
Current revision
Crystal structure of MhuD R26S mutant with two Manganese protoporphyrin IX bound per active site
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