This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5xyv

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:17, 22 November 2023) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
==Crystal structure of drosophila melanogaster Rhino chromoshadow domain in complex with Deadlock N-terminal domain==
==Crystal structure of drosophila melanogaster Rhino chromoshadow domain in complex with Deadlock N-terminal domain==
-
<StructureSection load='5xyv' size='340' side='right' caption='[[5xyv]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
+
<StructureSection load='5xyv' size='340' side='right'caption='[[5xyv]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5xyv]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XYV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XYV FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5xyv]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XYV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XYV FirstGlance]. <br>
-
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xyv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xyv OCA], [http://pdbe.org/5xyv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xyv RCSB], [http://www.ebi.ac.uk/pdbsum/5xyv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xyv ProSAT]</span></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xyv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xyv OCA], [https://pdbe.org/5xyv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xyv RCSB], [https://www.ebi.ac.uk/pdbsum/5xyv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xyv ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/DEL_DROME DEL_DROME]] Developmental protein involved in oogenesis (PubMed:16616913). Required for germline maintenance, stability of mitotic spindles, localization of patterning determinants, oocyte growth and fusome biogenesis in males and females (PubMed:16616913). Also required for dorso-ventral and antero-posterior patterning of oocyte and eggshell (PubMed:16616913). May be involved in microtubule function during oogenesis (PubMed:16616913). Part of a rhi-dependent transcription machinery that enables the generation of piRNA precursors from heterochromatin while maintaining the suppression of transposon-encoded promoters and enhancers (PubMed:28847004). Component of the RDC complex (rhi, del and cuff) which binds to repressive H3K9me3 marks in the piRNA clusters (PubMed:28847004). RDC promotes the bidirectional transcription of piRNA clusters at these sites by interacting with Moonshiner which forms a complex with the transcription initiation factors TfIIA-S and Trf2 (PubMed:28847004). This mechanism allows transcription to occur in piRNA clusters despite the lack of proper promoter elements and in the presence of the repressive H3K9me3 mark (PubMed:28847004).<ref>PMID:16616913</ref> <ref>PMID:28847004</ref>
+
[https://www.uniprot.org/uniprot/Q7JXA8_DROME Q7JXA8_DROME]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 21: Line 22:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Huang, Y]]
+
[[Category: Drosophila melanogaster]]
-
[[Category: Yu, B W]]
+
[[Category: Large Structures]]
-
[[Category: Chromoshadow]]
+
[[Category: Huang Y]]
-
[[Category: Complex]]
+
[[Category: Yu BW]]
-
[[Category: Pirna pathway]]
+
-
[[Category: Protein binding]]
+

Current revision

Crystal structure of drosophila melanogaster Rhino chromoshadow domain in complex with Deadlock N-terminal domain

PDB ID 5xyv

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5xyv"
Personal tools