6b4f
From Proteopedia
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==Crystal structure of human Gle1 CTD-Nup42 GBM complex== | ==Crystal structure of human Gle1 CTD-Nup42 GBM complex== | ||
| - | <StructureSection load='6b4f' size='340' side='right' caption='[[6b4f]], [[Resolution|resolution]] 2.81Å' scene=''> | + | <StructureSection load='6b4f' size='340' side='right'caption='[[6b4f]], [[Resolution|resolution]] 2.81Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6b4f]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B4F OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[6b4f]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B4F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6B4F FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.811Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6b4f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b4f OCA], [https://pdbe.org/6b4f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6b4f RCSB], [https://www.ebi.ac.uk/pdbsum/6b4f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6b4f ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/GLE1_HUMAN GLE1_HUMAN] Lethal arthrogryposis - anterior horn cell disease;Lethal congenital contracture syndrome type 1. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. |
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/GLE1_HUMAN GLE1_HUMAN] Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC).<ref>PMID:12668658</ref> <ref>PMID:16000379</ref> <ref>PMID:9618489</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Cai SW]] |
| - | [[Category: | + | [[Category: Correia AR]] |
| - | [[Category: | + | [[Category: Hoelz A]] |
| - | [[Category: | + | [[Category: Huber FM]] |
| - | [[Category: | + | [[Category: Jette CA]] |
| - | [[Category: | + | [[Category: Lin DH]] |
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Current revision
Crystal structure of human Gle1 CTD-Nup42 GBM complex
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Categories: Homo sapiens | Large Structures | Cai SW | Correia AR | Hoelz A | Huber FM | Jette CA | Lin DH
