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2jp2

From Proteopedia

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[[Image:2jp2.jpg|left|200px]]
 
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{{Structure
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==Solution structure and resonance assignment of the N-terminal EVH1 domain from the human Spred2 protein (Sprouty-related protein with EVH1 domain isoform 2)==
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|PDB= 2jp2 |SIZE=350|CAPTION= <scene name='initialview01'>2jp2</scene>
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<StructureSection load='2jp2' size='340' side='right'caption='[[2jp2]]' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[2jp2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JP2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JP2 FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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|GENE= SPRED2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jp2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jp2 OCA], [https://pdbe.org/2jp2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jp2 RCSB], [https://www.ebi.ac.uk/pdbsum/2jp2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jp2 ProSAT]</span></td></tr>
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|DOMAIN=
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</table>
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|RELATEDENTRY=
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== Function ==
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jp2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jp2 OCA], [http://www.ebi.ac.uk/pdbsum/2jp2 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2jp2 RCSB]</span>
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[https://www.uniprot.org/uniprot/SPRE2_HUMAN SPRE2_HUMAN] Tyrosine kinase substrate that inhibits growth-factor-mediated activation of MAP kinase.
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}}
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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'''Solution structure and resonance assignment of the N-terminal EVH1 domain from the human Spred2 protein (Sprouty-related protein with EVH1 domain isoform 2)'''
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jp/2jp2_consurf.spt"</scriptWhenChecked>
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==About this Structure==
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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2JP2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JP2 OCA].
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==Reference==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jp2 ConSurf].
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1H, 13C and 15N resonance assignment of the human Spred2 EVH1 domain., Zimmermann J, Jarchau T, Walter U, Oschkinat H, Ball LJ, J Biomol NMR. 2004 Jul;29(3):435-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15213456 15213456]
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Arrowsmith, C.]]
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[[Category: Arrowsmith C]]
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[[Category: Ball, L J.]]
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[[Category: Ball LJ]]
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[[Category: Edwards, A.]]
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[[Category: Edwards A]]
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[[Category: Fossi, M.]]
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[[Category: Fossi M]]
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[[Category: Jarchau, T.]]
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[[Category: Jarchau T]]
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[[Category: Lemak, A.]]
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[[Category: Lemak A]]
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[[Category: Oschkinat, H.]]
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[[Category: Oschkinat H]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Sundstrom M]]
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[[Category: Sundstrom, M.]]
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[[Category: Walter U]]
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[[Category: Walter, U.]]
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[[Category: Wiegelt J]]
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[[Category: Wiegelt, J.]]
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[[Category: Zimmermann J]]
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[[Category: Zimmermann, J.]]
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[[Category: evh1 domain]]
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[[Category: sgc]]
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[[Category: solution structure]]
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[[Category: structural genomic]]
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[[Category: structural genomics consortium]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:00:20 2008''
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Current revision

Solution structure and resonance assignment of the N-terminal EVH1 domain from the human Spred2 protein (Sprouty-related protein with EVH1 domain isoform 2)

PDB ID 2jp2

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