This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5o9v

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:37, 6 December 2023) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
==HsNMT1 in complex with CoA and Myristoylated-GGCFSKPK octapeptide==
==HsNMT1 in complex with CoA and Myristoylated-GGCFSKPK octapeptide==
-
<StructureSection load='5o9v' size='340' side='right' caption='[[5o9v]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
+
<StructureSection load='5o9v' size='340' side='right'caption='[[5o9v]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5o9v]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5O9V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5O9V FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5o9v]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5O9V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5O9V FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MYR:MYRISTIC+ACID'>MYR</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.201&#8491;</td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glycylpeptide_N-tetradecanoyltransferase Glycylpeptide N-tetradecanoyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.97 2.3.1.97] </span></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MYR:MYRISTIC+ACID'>MYR</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5o9v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5o9v OCA], [http://pdbe.org/5o9v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5o9v RCSB], [http://www.ebi.ac.uk/pdbsum/5o9v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5o9v ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5o9v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5o9v OCA], [https://pdbe.org/5o9v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5o9v RCSB], [https://www.ebi.ac.uk/pdbsum/5o9v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5o9v ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/NMT1_HUMAN NMT1_HUMAN]] Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. [[http://www.uniprot.org/uniprot/AIFM3_HUMAN AIFM3_HUMAN]] Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential.<ref>PMID:15764604</ref>
+
[https://www.uniprot.org/uniprot/NMT1_HUMAN NMT1_HUMAN] Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 23: Line 23:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Glycylpeptide N-tetradecanoyltransferase]]
+
[[Category: Homo sapiens]]
-
[[Category: Dian, C]]
+
[[Category: Large Structures]]
-
[[Category: Giglione, C]]
+
[[Category: Dian C]]
-
[[Category: Meinnel, T]]
+
[[Category: Giglione C]]
-
[[Category: Acyltransferase]]
+
[[Category: Meinnel T]]
-
[[Category: Coa]]
+
-
[[Category: Glycylpeptide n-tetradecanoyltransferase 1 n-myristoyltransferase 1]]
+
-
[[Category: Gnat]]
+
-
[[Category: Myr-coa]]
+
-
[[Category: Myr-peptide]]
+
-
[[Category: Myristoyl]]
+
-
[[Category: N-myristoyltransferase type1]]
+
-
[[Category: Nmt]]
+
-
[[Category: Nmt1]]
+
-
[[Category: Transferase]]
+

Current revision

HsNMT1 in complex with CoA and Myristoylated-GGCFSKPK octapeptide

PDB ID 5o9v

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5o9v"
Personal tools