6dwe

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'''Unreleased structure'''
 
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The entry 6dwe is ON HOLD
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==Crystal structure of tryptophan synthase from M. tuberculosis - aminoacrylate- and BRD0059-bound form==
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<StructureSection load='6dwe' size='340' side='right'caption='[[6dwe]], [[Resolution|resolution]] 2.69&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6dwe]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DWE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6DWE FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.691&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CS:CESIUM+ION'>CS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=HDJ:(2~{R},3~{S},4~{R})-3-[4-[2,6-bis(fluoranyl)-4-methyl-phenyl]phenyl]-4-(fluoranylmethyl)azetidine-2-carbonitrile'>HDJ</scene>, <scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=P1T:2-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]ACRYLIC+ACID'>P1T</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6dwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dwe OCA], [https://pdbe.org/6dwe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6dwe RCSB], [https://www.ebi.ac.uk/pdbsum/6dwe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6dwe ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TRPA_MYCTU TRPA_MYCTU] The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
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Authors: Chang, C., Michalska, K., Maltseva, N.I., Jedrzejczak, R., McCarren, P., Nag, P.P., Joachimiak, A., Satchell, K., Center for Structural Genomics of Infectious Diseases (CSGID)
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==See Also==
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*[[Tryptophan synthase 3D structures|Tryptophan synthase 3D structures]]
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Description: Crystal structure of tryptophan synthase from M. tuberculosis -aminoacrylate-and BRD0059-bound form
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__TOC__
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[[Category: Unreleased Structures]]
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</StructureSection>
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[[Category: Michalska, K]]
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[[Category: Large Structures]]
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[[Category: Mccarren, P]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Joachimiak, A]]
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[[Category: Chang C]]
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[[Category: Maltseva, N.I]]
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[[Category: Jedrzejczak R]]
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[[Category: Satchell, K]]
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[[Category: Joachimiak A]]
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[[Category: Jedrzejczak, R]]
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[[Category: Maltseva NI]]
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[[Category: Center For Structural Genomics Of Infectious Diseases (Csgid)]]
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[[Category: McCarren P]]
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[[Category: Chang, C]]
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[[Category: Michalska K]]
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[[Category: Nag, P.P]]
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[[Category: Nag PP]]
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[[Category: Satchell K]]

Current revision

Crystal structure of tryptophan synthase from M. tuberculosis - aminoacrylate- and BRD0059-bound form

PDB ID 6dwe

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