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1zni
From Proteopedia
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==INSULIN== | ==INSULIN== | ||
| - | <StructureSection load='1zni' size='340' side='right' caption='[[1zni]], [[Resolution|resolution]] 1.50Å' scene=''> | + | <StructureSection load='1zni' size='340' side='right'caption='[[1zni]], [[Resolution|resolution]] 1.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1zni]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1zni]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZNI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZNI FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.498Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zni FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zni OCA], [https://pdbe.org/1zni PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zni RCSB], [https://www.ebi.ac.uk/pdbsum/1zni PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zni ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/INS_PIG INS_PIG] Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
| - | *[[ | + | *[[Insulin 3D Structures|Insulin 3D Structures]] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Sus scrofa]] | [[Category: Sus scrofa]] | ||
| - | [[Category: Bentley | + | [[Category: Bentley GA]] |
| - | [[Category: Dodson | + | [[Category: Dodson EJ]] |
| - | [[Category: Dodson | + | [[Category: Dodson GG]] |
| - | [[Category: Turkenburg | + | [[Category: Turkenburg MGW]] |
| - | [[Category: Whittingham | + | [[Category: Whittingham JL]] |
| - | [[Category: Xiao | + | [[Category: Xiao B]] |
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Current revision
INSULIN
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