This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2i1p

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:27, 14 June 2023) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
==Solution structure of the twelfth cysteine-rich ligand-binding repeat in rat megalin==
==Solution structure of the twelfth cysteine-rich ligand-binding repeat in rat megalin==
-
<StructureSection load='2i1p' size='340' side='right' caption='[[2i1p]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
+
<StructureSection load='2i1p' size='340' side='right'caption='[[2i1p]]' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2i1p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I1P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2I1P FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2i1p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I1P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I1P FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2i1p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i1p OCA], [http://pdbe.org/2i1p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2i1p RCSB], [http://www.ebi.ac.uk/pdbsum/2i1p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2i1p ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i1p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i1p OCA], [https://pdbe.org/2i1p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i1p RCSB], [https://www.ebi.ac.uk/pdbsum/2i1p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i1p ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/LRP2_RAT LRP2_RAT]] Acts together with cubilin to mediate HDL endocytosis (By similarity). Receptor-mediated uptake of polybasic drugs such as aprotinin, aminoglycosides and polymyxin B.<ref>PMID:7544804</ref>
+
[https://www.uniprot.org/uniprot/LRP2_RAT LRP2_RAT] Acts together with cubilin to mediate HDL endocytosis (By similarity). Receptor-mediated uptake of polybasic drugs such as aprotinin, aminoglycosides and polymyxin B.<ref>PMID:7544804</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 32: Line 32:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Buffalo rat]]
+
[[Category: Large Structures]]
-
[[Category: Bade-Noskova, V]]
+
[[Category: Rattus norvegicus]]
-
[[Category: Dancea, F]]
+
[[Category: Bade-Noskova V]]
-
[[Category: Kerjaschki, D]]
+
[[Category: Dancea F]]
-
[[Category: Luecke, C]]
+
[[Category: Kerjaschki D]]
-
[[Category: Rueterjans, H]]
+
[[Category: Luecke C]]
-
[[Category: Shi, M]]
+
[[Category: Rueterjans H]]
-
[[Category: Wolf, C A]]
+
[[Category: Shi M]]
-
[[Category: Calcium cage]]
+
[[Category: Wolf CA]]
-
[[Category: Cysteine-rich repeat]]
+
-
[[Category: Ligand binding domain]]
+
-
[[Category: Ligand binding protein]]
+
-
[[Category: Low density lipoprotein receptor]]
+

Current revision

Solution structure of the twelfth cysteine-rich ligand-binding repeat in rat megalin

PDB ID 2i1p

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2i1p"
Personal tools