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2ist
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==crystal structure of RluD from E. coli== | ==crystal structure of RluD from E. coli== | ||
| - | <StructureSection load='2ist' size='340' side='right' caption='[[2ist]], [[Resolution|resolution]] 1.86Å' scene=''> | + | <StructureSection load='2ist' size='340' side='right'caption='[[2ist]], [[Resolution|resolution]] 1.86Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2ist]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2ist]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IST OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IST FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.86Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BCT:BICARBONATE+ION'>BCT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> |
| - | < | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ist FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ist OCA], [https://pdbe.org/2ist PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ist RCSB], [https://www.ebi.ac.uk/pdbsum/2ist PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ist ProSAT]</span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/RLUD_ECOLI RLUD_ECOLI] Responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA. Isomerization occurs as a late step during the assembly of the large ribosomal subunit.<ref>PMID:11087118</ref> <ref>PMID:17937767</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
| - | *[[ | + | *[[Guide-independent Pseudouridine synthase|Guide-independent Pseudouridine synthase]] |
| + | *[[Pseudouridine synthase 3D structures|Pseudouridine synthase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Escherichia coli]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Finer-Moore JS]] |
| - | + | [[Category: Foster PG]] | |
| - | + | [[Category: Stroud RM]] | |
| - | [[Category: | + | |
| - | [[Category: | + | |
| - | + | ||
Current revision
crystal structure of RluD from E. coli
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