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2iy6

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==1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE FROM THERMUS WITH BOUND CITRATE==
==1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE FROM THERMUS WITH BOUND CITRATE==
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<StructureSection load='2iy6' size='340' side='right' caption='[[2iy6]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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<StructureSection load='2iy6' size='340' side='right'caption='[[2iy6]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2iy6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IY6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IY6 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2iy6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IY6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IY6 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2bhp|2bhp]], [[2bhq|2bhq]], [[2bja|2bja]], [[2bjk|2bjk]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/1-pyrroline-5-carboxylate_dehydrogenase 1-pyrroline-5-carboxylate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.12 1.5.1.12] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iy6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iy6 OCA], [https://pdbe.org/2iy6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iy6 RCSB], [https://www.ebi.ac.uk/pdbsum/2iy6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iy6 ProSAT], [https://www.topsan.org/Proteins/RSGI/2iy6 TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iy6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iy6 OCA], [http://pdbe.org/2iy6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2iy6 RCSB], [http://www.ebi.ac.uk/pdbsum/2iy6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2iy6 ProSAT], [http://www.topsan.org/Proteins/RSGI/2iy6 TOPSAN]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q5SI02_THET8 Q5SI02_THET8]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 1-pyrroline-5-carboxylate dehydrogenase]]
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[[Category: Large Structures]]
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[[Category: Thet8]]
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[[Category: Thermus thermophilus HB8]]
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[[Category: Inagaki, E]]
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[[Category: Inagaki E]]
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[[Category: Nishio, M]]
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[[Category: Nishio M]]
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[[Category: Sakamoto, K]]
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[[Category: Sakamoto K]]
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[[Category: Yokoyama, S]]
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[[Category: Yokoyama S]]
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[[Category: 1-pyrroline-5-carboxylate]]
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[[Category: Citrate]]
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[[Category: Dehyrogenase]]
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[[Category: Oxidoreductase]]
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[[Category: Structural genomic]]
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[[Category: Rsgi]]
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Current revision

1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE FROM THERMUS WITH BOUND CITRATE

PDB ID 2iy6

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