6a89
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the ternary complex of peptidoglycan recognition protein (PGRP-S) with Tartaric acid, Ribose and 2,6-DIAMINOPIMELIC ACID at 2.11 A resolution== | |
| - | + | <StructureSection load='6a89' size='340' side='right'caption='[[6a89]], [[Resolution|resolution]] 2.11Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6a89]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Camelus_dromedarius Camelus dromedarius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6A89 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6A89 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.11Å</td></tr> | |
| - | [[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=API:2,6-DIAMINOPIMELIC+ACID'>API</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=RIB:RIBOSE'>RIB</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr> |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6a89 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6a89 OCA], [https://pdbe.org/6a89 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6a89 RCSB], [https://www.ebi.ac.uk/pdbsum/6a89 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6a89 ProSAT]</span></td></tr> |
| - | [[ | + | </table> |
| - | [[Category: Bairagya | + | == Function == |
| - | [[Category: Sharma | + | [https://www.uniprot.org/uniprot/PGRP1_CAMDR PGRP1_CAMDR] Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria. Involved in innate immunity. Is microbicidal for Gram-positive and Gram-negative bacteria and yeast. May function in intracellular killing of bacteria (By similarity). |
| - | [[Category: Sharma | + | __TOC__ |
| - | [[Category: Singh | + | </StructureSection> |
| + | [[Category: Camelus dromedarius]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Bairagya HR]] | ||
| + | [[Category: Sharma P]] | ||
| + | [[Category: Sharma S]] | ||
| + | [[Category: Shokeen A]] | ||
| + | [[Category: Singh PK]] | ||
| + | [[Category: Singh TP]] | ||
Current revision
Crystal structure of the ternary complex of peptidoglycan recognition protein (PGRP-S) with Tartaric acid, Ribose and 2,6-DIAMINOPIMELIC ACID at 2.11 A resolution
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