6bwd

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:43, 4 June 2025) (edit) (undo)
 
(5 intermediate revisions not shown.)
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 6bwd is ON HOLD until Paper Publication
+
==3.7 angstrom cryoEM structure of truncated mouse TRPM7==
-
 
+
<SX load='6bwd' size='340' side='right' viewer='molstar' caption='[[6bwd]], [[Resolution|resolution]] 3.70&Aring;' scene=''>
-
Authors:
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[6bwd]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BWD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6BWD FirstGlance]. <br>
-
Description:
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.7&#8491;</td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=Y01:CHOLESTEROL+HEMISUCCINATE'>Y01</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6bwd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bwd OCA], [https://pdbe.org/6bwd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6bwd RCSB], [https://www.ebi.ac.uk/pdbsum/6bwd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6bwd ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/TRPM7_MOUSE TRPM7_MOUSE] Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium. Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1).<ref>PMID:11385574</ref>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</SX>
 +
[[Category: Large Structures]]
 +
[[Category: Mus musculus]]
 +
[[Category: Abiria SA]]
 +
[[Category: Clapham DE]]
 +
[[Category: Duan J]]
 +
[[Category: Hulse RE]]
 +
[[Category: Krapivinsky G]]
 +
[[Category: Li J]]
 +
[[Category: Li Z]]
 +
[[Category: Santa-Cruz A]]
 +
[[Category: Zhang J]]

Current revision

3.7 angstrom cryoEM structure of truncated mouse TRPM7

6bwd, resolution 3.70Å

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/6bwd"
Personal tools