This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6e0k
From Proteopedia
(Difference between revisions)
m (Protected "6e0k" [edit=sysop:move=sysop]) |
|||
| (4 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Structure of Rhodothermus marinus CdnE c-UMP-AMP synthase== | |
| - | + | <StructureSection load='6e0k' size='340' side='right'caption='[[6e0k]], [[Resolution|resolution]] 1.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6e0k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodothermus_marinus_SG0.5JP17-172 Rhodothermus marinus SG0.5JP17-172]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6E0K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6E0K FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6e0k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6e0k OCA], [https://pdbe.org/6e0k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6e0k RCSB], [https://www.ebi.ac.uk/pdbsum/6e0k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6e0k ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CDNE_RHOMG CDNE_RHOMG] CBASS (cyclic oligonucleotide-based antiphage signaling system) provides immunity against bacteriophage. The CD-NTase protein synthesizes cyclic nucleotides in response to infection; these serve as specific second messenger signals. The signals activate a diverse range of effectors, leading to bacterial cell death and thus abortive phage infection. A type I-B(UU) CBASS system (PubMed:32839535).<ref>PMID:32839535</ref> Cyclic dinucleotide synthase that catalyzes the synthesis of 3'3'-cyclic UMP-AMP (cUMP-AMP) from UTP and ATP, a second messenger for cell signal transduction.<ref>PMID:30787435</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Rhodothermus marinus SG0 5JP17-172]] | ||
| + | [[Category: Eaglesham JB]] | ||
| + | [[Category: King DS]] | ||
| + | [[Category: Kranzusch PJ]] | ||
| + | [[Category: Lee ASY]] | ||
| + | [[Category: Mekalanos JJ]] | ||
| + | [[Category: Morehouse BR]] | ||
| + | [[Category: Nieminen EA]] | ||
| + | [[Category: Whiteley AT]] | ||
| + | [[Category: De Oliveira Mann CC]] | ||
Current revision
Structure of Rhodothermus marinus CdnE c-UMP-AMP synthase
| |||||||||||
