6h1q
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Proteus mirabilis Ambient Temperature Fimbriae adhesin AtfE== | |
| + | <StructureSection load='6h1q' size='340' side='right'caption='[[6h1q]], [[Resolution|resolution]] 1.58Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6h1q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Proteus_mirabilis_HI4320 Proteus mirabilis HI4320]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6H1Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6H1Q FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.58Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6h1q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6h1q OCA], [https://pdbe.org/6h1q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6h1q RCSB], [https://www.ebi.ac.uk/pdbsum/6h1q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6h1q ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The important uropathogen Proteus mirabilis encodes a record number of chaperone/usher-pathway adhesive fimbriae. Such fimbriae, which are used for adhesion to cell surfaces/tissues and for biofilm formation, are typically important virulence factors in bacterial pathogenesis. Here, the structures of the receptor-binding domains of the tip-located two-domain adhesins UcaD (1.5 A resolution) and AtfE (1.58 A resolution) from two P. mirabilis fimbriae (UCA/NAF and ATF) are presented. The structures of UcaD and AtfE are both similar to the F17G type of tip-located fimbrial receptor-binding domains, and the structures are very similar despite having only limited sequence similarity. These structures represent an important step towards a molecular-level understanding of P. mirabilis fimbrial adhesins and their roles in the complex pathogenesis of urinary-tract infections. | ||
| - | + | Structures of two fimbrial adhesins, AtfE and UcaD, from the uropathogen Proteus mirabilis.,Jiang W, Ubhayasekera W, Pearson MM, Knight SD Acta Crystallogr D Struct Biol. 2018 Nov 1;74(Pt 11):1053-1062. doi:, 10.1107/S2059798318012391. Epub 2018 Oct 29. PMID:30387764<ref>PMID:30387764</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | [[Category: | + | </div> |
| + | <div class="pdbe-citations 6h1q" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Adhesin 3D structures|Adhesin 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Proteus mirabilis HI4320]] | ||
| + | [[Category: Knight SD]] | ||
| + | [[Category: Wangshu J]] | ||
Current revision
Proteus mirabilis Ambient Temperature Fimbriae adhesin AtfE
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