5xz3

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:17, 22 November 2023) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
==The X-ray structure of Apis mellifera PGRP-SA==
==The X-ray structure of Apis mellifera PGRP-SA==
-
<StructureSection load='5xz3' size='340' side='right' caption='[[5xz3]], [[Resolution|resolution]] 1.86&Aring;' scene=''>
+
<StructureSection load='5xz3' size='340' side='right'caption='[[5xz3]], [[Resolution|resolution]] 1.86&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5xz3]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XZ3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XZ3 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5xz3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Apis_mellifera Apis mellifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XZ3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XZ3 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.86&#8491;</td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xz3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xz3 OCA], [http://pdbe.org/5xz3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xz3 RCSB], [http://www.ebi.ac.uk/pdbsum/5xz3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xz3 ProSAT]</span></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xz3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xz3 OCA], [https://pdbe.org/5xz3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xz3 RCSB], [https://www.ebi.ac.uk/pdbsum/5xz3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xz3 ProSAT]</span></td></tr>
</table>
</table>
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
Peptidoglycan recognition protein SA (PGRP-SA) is a key pattern recognition receptor in the insect innate immune system. PGRP-SA can bind to bacterial PGN and activate the Toll pathway, which triggers the expression and release of antimicrobial peptides to prevent bacterial infection. Here, we report the first structure of Apis mellifera PGRP-SA from Hymenoptera at 1.86 A resolution. The overall architecture of Am-PGRP-SA was similar to the Drosophila PGRP-SA; however, the residues involved in PGN binding groove were not conserved, and the binding pocket was narrower. This structure gives insight into PGN binding characteristics in honeybees.
 +
 +
Crystal structure of peptidoglycan recognition protein SA in Apis mellifera (Hymenoptera: Apidae).,Liu Y, Zhao X, Naeem M, An J Protein Sci. 2018 Apr;27(4):893-897. doi: 10.1002/pro.3383. Epub 2018 Mar 14. PMID:29396863<ref>PMID:29396863</ref>
 +
 +
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 +
</div>
 +
<div class="pdbe-citations 5xz3" style="background-color:#fffaf0;"></div>
 +
== References ==
 +
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: An, J D]]
 
-
[[Category: Huang, J X]]
 
-
[[Category: Liu, Y J]]
 
-
[[Category: Zhao, X M]]
 
[[Category: Apis mellifera]]
[[Category: Apis mellifera]]
-
[[Category: Immune system]]
+
[[Category: Large Structures]]
-
[[Category: Pgrp-sa]]
+
[[Category: An JD]]
 +
[[Category: Huang JX]]
 +
[[Category: Liu YJ]]
 +
[[Category: Zhao XM]]

Current revision

The X-ray structure of Apis mellifera PGRP-SA

PDB ID 5xz3

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5xz3"
Personal tools