2p8w

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==Fitted structure of eEF2 in the 80S:eEF2:GDPNP cryo-EM reconstruction==
==Fitted structure of eEF2 in the 80S:eEF2:GDPNP cryo-EM reconstruction==
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<StructureSection load='2p8w' size='340' side='right' caption='[[2p8w]], [[Resolution|resolution]] 11.30&Aring;' scene=''>
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<SX load='2p8w' size='340' side='right' viewer='molstar' caption='[[2p8w]], [[Resolution|resolution]] 11.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2p8w]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] and [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P8W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2P8W FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2p8w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] and [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P8W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2P8W FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 11.3&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1k5x|1k5x]], [[1k5y|1k5y]], [[2p8x|2p8x]], [[2p8y|2p8y]], [[2p8z|2p8z]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2p8w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p8w OCA], [http://pdbe.org/2p8w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2p8w RCSB], [http://www.ebi.ac.uk/pdbsum/2p8w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2p8w ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p8w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p8w OCA], [https://pdbe.org/2p8w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p8w RCSB], [https://www.ebi.ac.uk/pdbsum/2p8w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p8w ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/EFTU2_THET8 EFTU2_THET8]] This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
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[https://www.uniprot.org/uniprot/EF2_YEAST EF2_YEAST]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p8/2p8w_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p8/2p8w_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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==See Also==
==See Also==
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*[[Elongation factor|Elongation factor]]
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*[[Elongation factor 3D structures|Elongation factor 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
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</StructureSection>
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</SX>
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[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
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[[Category: Andersen, G R]]
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[[Category: Andersen GR]]
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[[Category: Frank, J]]
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[[Category: Frank J]]
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[[Category: Merrill, A R]]
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[[Category: Merrill AR]]
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[[Category: Nilsson, J]]
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[[Category: Nilsson J]]
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[[Category: Nissen, P]]
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[[Category: Nissen P]]
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[[Category: Taylor, D J]]
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[[Category: Taylor DJ]]
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[[Category: 80s ribosome]]
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[[Category: Elongation]]
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[[Category: Gtpase]]
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[[Category: Translation]]
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[[Category: Translocation]]
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Current revision

Fitted structure of eEF2 in the 80S:eEF2:GDPNP cryo-EM reconstruction

2p8w, resolution 11.30Å

Proteopedia Page Contributors and Editors (what is this?)

OCA

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