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2bgs

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[[Image:2bgs.gif|left|200px]]<br />
 
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<applet load="2bgs" size="450" color="white" frame="true" align="right" spinBox="true"
 
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caption="2bgs, resolution 1.64&Aring;" />
 
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'''HOLO ALDOSE REDUCTASE FROM BARLEY'''<br />
 
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==About this Structure==
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==HOLO ALDOSE REDUCTASE FROM BARLEY==
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2BGS is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Hordeum_vulgare Hordeum vulgare] with BCT, SO4 and NDP as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21] Structure known Active Site: AC1. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2BGS OCA].
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<StructureSection load='2bgs' size='340' side='right'caption='[[2bgs]], [[Resolution|resolution]] 1.64&Aring;' scene=''>
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[[Category: Aldehyde reductase]]
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== Structural highlights ==
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[[Category: Hordeum vulgare]]
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<table><tr><td colspan='2'>[[2bgs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Hordeum_vulgare Hordeum vulgare]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BGS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BGS FirstGlance]. <br>
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[[Category: Single protein]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.64&#8491;</td></tr>
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[[Category: Christensen, C.L.]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BCT:BICARBONATE+ION'>BCT</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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[[Category: Henriksen, A.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bgs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bgs OCA], [https://pdbe.org/2bgs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bgs RCSB], [https://www.ebi.ac.uk/pdbsum/2bgs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bgs ProSAT]</span></td></tr>
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[[Category: Olsen, J.G.]]
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</table>
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[[Category: Olsen, O.]]
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== Function ==
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[[Category: Pedersen, L.]]
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[https://www.uniprot.org/uniprot/ALDR_HORVU ALDR_HORVU]
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[[Category: BCT]]
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== Evolutionary Conservation ==
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[[Category: NDP]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: SO4]]
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Check<jmol>
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[[Category: aldo/keto reductase]]
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<jmolCheckbox>
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[[Category: aldose reductase]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bg/2bgs_consurf.spt"</scriptWhenChecked>
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[[Category: holoenzyme]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: oxidoreductase]]
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2bgs ConSurf].
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<div style="clear:both"></div>
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Nov 5 17:37:51 2007''
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==See Also==
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*[[Aldose reductase 3D structures|Aldose reductase 3D structures]]
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__TOC__
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</StructureSection>
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[[Category: Hordeum vulgare]]
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[[Category: Large Structures]]
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[[Category: Christensen CL]]
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[[Category: Henriksen A]]
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[[Category: Olsen JG]]
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[[Category: Olsen O]]
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[[Category: Pedersen L]]

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