2k17
From Proteopedia
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==Solution structure of the TAF3 PHD domain in complex with a H3K4me3 peptide== | ==Solution structure of the TAF3 PHD domain in complex with a H3K4me3 peptide== | ||
| - | <StructureSection load='2k17' size='340' side='right' caption='[[2k17 | + | <StructureSection load='2k17' size='340' side='right'caption='[[2k17]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2k17]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2k17]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K17 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K17 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=M3L:N-TRIMETHYLLYSINE'>M3L</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k17 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k17 OCA], [https://pdbe.org/2k17 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k17 RCSB], [https://www.ebi.ac.uk/pdbsum/2k17 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k17 ProSAT]</span></td></tr> | |
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| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/TAF3_MOUSE TAF3_MOUSE] Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Required in complex with TBPL2 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process.<ref>PMID:17704303</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Boelens | + | [[Category: Boelens R]] |
| - | + | [[Category: Timmers M]] | |
| - | + | [[Category: Wienk H]] | |
| - | [[Category: Timmers | + | [[Category: Van Ingen H]] |
| - | [[Category: Wienk | + | [[Category: Van Schaik FMA]] |
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Current revision
Solution structure of the TAF3 PHD domain in complex with a H3K4me3 peptide
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