6gs6
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Cyclophilin A single mutant D66A in complex with an inhibitor.== | |
| - | + | <StructureSection load='6gs6' size='340' side='right'caption='[[6gs6]], [[Resolution|resolution]] 1.16Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6gs6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GS6 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6GS6 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EA4:ETHYL+N-[(4-AMINOBENZYL)CARBAMOYL]GLYCINATE'>EA4</scene></td></tr> | |
| - | [[Category: | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PPIA, CYPA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidylprolyl_isomerase Peptidylprolyl isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6gs6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gs6 OCA], [http://pdbe.org/6gs6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gs6 RCSB], [http://www.ebi.ac.uk/pdbsum/6gs6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gs6 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PPIA_HUMAN PPIA_HUMAN]] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Peptidylprolyl isomerase]] | ||
| + | [[Category: Georgiou, C]] | ||
[[Category: Juarez-Jimenez, J]] | [[Category: Juarez-Jimenez, J]] | ||
| - | [[Category: Georgiou, C]] | ||
[[Category: Michel, J]] | [[Category: Michel, J]] | ||
| - | [[Category: | + | [[Category: Simone, A De]] |
| - | [[Category: Walkinshaw, M | + | [[Category: Walkinshaw, M D]] |
| + | [[Category: Complex]] | ||
| + | [[Category: Cyclophilin]] | ||
| + | [[Category: Cypa]] | ||
| + | [[Category: Cypa mutant]] | ||
| + | [[Category: Inhibitor]] | ||
| + | [[Category: Isomerase]] | ||
| + | [[Category: Ppiase]] | ||
Current revision
Cyclophilin A single mutant D66A in complex with an inhibitor.
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Categories: Human | Large Structures | Peptidylprolyl isomerase | Georgiou, C | Juarez-Jimenez, J | Michel, J | Simone, A De | Walkinshaw, M D | Complex | Cyclophilin | Cypa | Cypa mutant | Inhibitor | Isomerase | Ppiase
