6dxp

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==The crystal structure of an FMN-dependent NADH-azoreductase from Klebsiella pneumoniae==
==The crystal structure of an FMN-dependent NADH-azoreductase from Klebsiella pneumoniae==
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<StructureSection load='6dxp' size='340' side='right' caption='[[6dxp]], [[Resolution|resolution]] 2.48&Aring;' scene=''>
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<StructureSection load='6dxp' size='340' side='right'caption='[[6dxp]], [[Resolution|resolution]] 2.48&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6dxp]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DXP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DXP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6dxp]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DXP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6DXP FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.478&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dxp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dxp OCA], [http://pdbe.org/6dxp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dxp RCSB], [http://www.ebi.ac.uk/pdbsum/6dxp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dxp ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6dxp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dxp OCA], [https://pdbe.org/6dxp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6dxp RCSB], [https://www.ebi.ac.uk/pdbsum/6dxp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6dxp ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/A0A1W1JPX6_KLEPN A0A1W1JPX6_KLEPN]] Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity.[HAMAP-Rule:MF_01216][SAAS:SAAS00096932]
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[https://www.uniprot.org/uniprot/A6TCS9_KLEP7 A6TCS9_KLEP7] Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.[HAMAP-Rule:MF_01216] Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.[HAMAP-Rule:MF_01216]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Almo, S C]]
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[[Category: Klebsiella pneumoniae]]
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[[Category: Arcinas, A J]]
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[[Category: Large Structures]]
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[[Category: Bonanno, J B]]
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[[Category: Almo SC]]
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[[Category: Chamala, S]]
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[[Category: Arcinas AJ]]
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[[Category: Ghosh, A]]
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[[Category: Bonanno JB]]
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[[Category: Kelly, L]]
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[[Category: Chamala S]]
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[[Category: Azoreductase]]
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[[Category: Ghosh A]]
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[[Category: Oxidoreductase]]
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[[Category: Kelly L]]

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The crystal structure of an FMN-dependent NADH-azoreductase from Klebsiella pneumoniae

PDB ID 6dxp

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