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5y1w

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==Crystal structure of Plasmodium falciparum aminopeptidase N with Magnesium bound to active site Zinc==
==Crystal structure of Plasmodium falciparum aminopeptidase N with Magnesium bound to active site Zinc==
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<StructureSection load='5y1w' size='340' side='right' caption='[[5y1w]], [[Resolution|resolution]] 1.56&Aring;' scene=''>
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<StructureSection load='5y1w' size='340' side='right'caption='[[5y1w]], [[Resolution|resolution]] 1.56&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5y1w]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Y1W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5Y1W FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5y1w]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_FcB1/Columbia Plasmodium falciparum FcB1/Columbia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Y1W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5Y1W FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.56&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5y1w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5y1w OCA], [http://pdbe.org/5y1w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5y1w RCSB], [http://www.ebi.ac.uk/pdbsum/5y1w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5y1w ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5y1w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5y1w OCA], [https://pdbe.org/5y1w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5y1w RCSB], [https://www.ebi.ac.uk/pdbsum/5y1w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5y1w ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/AMP1_PLAFQ AMP1_PLAFQ]] Displays aminopeptidase activity with a broad substrate specificity. Preferentially hydrolyzes L-Lys-AMC but also shows strong activity against L-Ala-AMC, L-Arg-AMC and L-Leu-AMC.<ref>PMID:12166515</ref> <ref>PMID:19196988</ref>
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[https://www.uniprot.org/uniprot/AMP1_PLAFQ AMP1_PLAFQ] Displays aminopeptidase activity with a broad substrate specificity. Preferentially hydrolyzes L-Lys-AMC but also shows strong activity against L-Ala-AMC, L-Arg-AMC and L-Leu-AMC.<ref>PMID:12166515</ref> <ref>PMID:19196988</ref>
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==See Also==
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*[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Addlagatta, A]]
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[[Category: Large Structures]]
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[[Category: Marapaka, A K]]
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[[Category: Plasmodium falciparum FcB1/Columbia]]
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[[Category: Hydrolase]]
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[[Category: Addlagatta A]]
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[[Category: M1-class aminopeptidase]]
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[[Category: Marapaka AK]]

Current revision

Crystal structure of Plasmodium falciparum aminopeptidase N with Magnesium bound to active site Zinc

PDB ID 5y1w

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