2ok3

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[[Image:2ok3.jpg|left|200px]]
 
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{{Structure
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==X-ray structure of human cyclophilin J at 2.0 angstrom==
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|PDB= 2ok3 |SIZE=350|CAPTION= <scene name='initialview01'>2ok3</scene>, resolution 2.00&Aring;
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<StructureSection load='2ok3' size='340' side='right'caption='[[2ok3]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>
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<table><tr><td colspan='2'>[[2ok3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OK3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OK3 FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidylprolyl_isomerase Peptidylprolyl isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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|GENE= PPIL3b ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ok3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ok3 OCA], [https://pdbe.org/2ok3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ok3 RCSB], [https://www.ebi.ac.uk/pdbsum/2ok3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ok3 ProSAT]</span></td></tr>
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|RELATEDENTRY=[[1xyh|1XYH]]
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ok3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ok3 OCA], [http://www.ebi.ac.uk/pdbsum/2ok3 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2ok3 RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/PPIL3_HUMAN PPIL3_HUMAN] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be involved in pre-mRNA splicing.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ok/2ok3_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ok3 ConSurf].
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<div style="clear:both"></div>
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'''X-ray structure of human cyclophilin J at 2.0 angstrom'''
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==See Also==
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*[[Cyclophilin 3D structures|Cyclophilin 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2OK3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OK3 OCA].
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Peptidylprolyl isomerase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Xia Z]]
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[[Category: Xia, Z.]]
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[[Category: beta-barrel]]
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[[Category: disulfide bridge]]
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[[Category: helix]]
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[[Category: isomerase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:18:56 2008''
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Current revision

X-ray structure of human cyclophilin J at 2.0 angstrom

PDB ID 2ok3

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