2lqy
From Proteopedia
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==Structure and orientation of the gH625-644 membrane interacting region of herpes simplex virus type 1 in a membrane mimetic system.== | ==Structure and orientation of the gH625-644 membrane interacting region of herpes simplex virus type 1 in a membrane mimetic system.== | ||
| - | <StructureSection load='2lqy' size='340' side='right' caption='[[2lqy | + | <StructureSection load='2lqy' size='340' side='right'caption='[[2lqy]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2lqy]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LQY OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[2lqy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_alphaherpesvirus_1 Human alphaherpesvirus 1]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LQY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LQY FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lqy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lqy OCA], [https://pdbe.org/2lqy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lqy RCSB], [https://www.ebi.ac.uk/pdbsum/2lqy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lqy ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GH_HHV11 GH_HHV11] The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL. May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis.[HAMAP-Rule:MF_04033]<ref>PMID:17548810</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Cantisani | + | [[Category: Human alphaherpesvirus 1]] |
| - | [[Category: Falanga | + | [[Category: Large Structures]] |
| - | [[Category: Fattorusso | + | [[Category: Cantisani M]] |
| - | [[Category: Galdiero | + | [[Category: Falanga A]] |
| - | [[Category: Galdiero | + | [[Category: Fattorusso R]] |
| - | [[Category: Isernia | + | [[Category: Galdiero M]] |
| - | [[Category: Malgieri | + | [[Category: Galdiero S]] |
| - | [[Category: Russo | + | [[Category: Isernia C]] |
| - | [[Category: Vitiello | + | [[Category: Malgieri G]] |
| - | + | [[Category: Russo L]] | |
| + | [[Category: Vitiello M]] | ||
Current revision
Structure and orientation of the gH625-644 membrane interacting region of herpes simplex virus type 1 in a membrane mimetic system.
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