2lfe
From Proteopedia
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==Solution NMR structure of N-terminal domain of human E3 ubiquitin-protein ligase HECW2, Northeast structural genomics consortium (NESG) target ht6306A== | ==Solution NMR structure of N-terminal domain of human E3 ubiquitin-protein ligase HECW2, Northeast structural genomics consortium (NESG) target ht6306A== | ||
| - | <StructureSection load='2lfe' size='340' side='right' caption='[[2lfe | + | <StructureSection load='2lfe' size='340' side='right'caption='[[2lfe]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2lfe]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2lfe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LFE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LFE FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lfe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lfe OCA], [https://pdbe.org/2lfe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lfe RCSB], [https://www.ebi.ac.uk/pdbsum/2lfe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lfe ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/HECW2_HUMAN HECW2_HUMAN] E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73. |
==See Also== | ==See Also== | ||
| - | *[[Ubiquitin protein ligase|Ubiquitin protein ligase]] | + | *[[Ubiquitin protein ligase 3D structures|Ubiquitin protein ligase 3D structures]] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Arrowsmith | + | [[Category: Large Structures]] |
| - | [[Category: Chitayat | + | [[Category: Arrowsmith C]] |
| - | [[Category: Dhe-Paganon | + | [[Category: Chitayat S]] |
| - | [[Category: Garcia | + | [[Category: Dhe-Paganon S]] |
| - | [[Category: Houliston | + | [[Category: Garcia M]] |
| - | [[Category: Lemak | + | [[Category: Houliston S]] |
| - | [[Category: Montelione | + | [[Category: Lemak A]] |
| - | + | [[Category: Montelione GT]] | |
| - | [[Category: Yee | + | [[Category: Yee A]] |
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Current revision
Solution NMR structure of N-terminal domain of human E3 ubiquitin-protein ligase HECW2, Northeast structural genomics consortium (NESG) target ht6306A
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