6h6t
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Binary crystal structure of positively and negatively supercharged variants Ftn(pos) and Ftn(neg) from human heavy chain ferritin (propandiol condition, coordination number 8)== | |
| - | + | <StructureSection load='6h6t' size='340' side='right'caption='[[6h6t]], [[Resolution|resolution]] 1.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6h6t]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6H6T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6H6T FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferroxidase Ferroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.16.3.1 1.16.3.1] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6h6t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6h6t OCA], [http://pdbe.org/6h6t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6h6t RCSB], [http://www.ebi.ac.uk/pdbsum/6h6t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6h6t ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/FRIH_HUMAN FRIH_HUMAN]] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Ferroxidase]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Beck, T]] | ||
| + | [[Category: Kuenzle, M]] | ||
| + | [[Category: Lach, M]] | ||
| + | [[Category: Binary nanoparticle superlattice]] | ||
| + | [[Category: Binary protein structure]] | ||
| + | [[Category: Charged protein container]] | ||
| + | [[Category: Oxidoreductase]] | ||
| + | [[Category: Protein design]] | ||
| + | [[Category: Protein engineering]] | ||
| + | [[Category: Self-assembly]] | ||
Current revision
Binary crystal structure of positively and negatively supercharged variants Ftn(pos) and Ftn(neg) from human heavy chain ferritin (propandiol condition, coordination number 8)
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