5zb3
From Proteopedia
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==Dimeric crystal structure of ORF57 from KSHV== | ==Dimeric crystal structure of ORF57 from KSHV== | ||
| - | <StructureSection load='5zb3' size='340' side='right' caption='[[5zb3]], [[Resolution|resolution]] 3.51Å' scene=''> | + | <StructureSection load='5zb3' size='340' side='right'caption='[[5zb3]], [[Resolution|resolution]] 3.51Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5zb3]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZB3 OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[5zb3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_gammaherpesvirus_8 Human gammaherpesvirus 8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZB3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ZB3 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.506Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5zb3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zb3 OCA], [https://pdbe.org/5zb3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5zb3 RCSB], [https://www.ebi.ac.uk/pdbsum/5zb3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5zb3 ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ICP27_HHV8P ICP27_HHV8P] Early protein that promotes the accumulation and nuclear export of viral intronless RNA transcripts by interacting with mRNAs and cellular export proteins. Probably acts as a viral splicing factor that regulates viral RNA splicing. Functions as a multifunctional regulator of the expression of viral lytic genes.<ref>PMID:15155762</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Human gammaherpesvirus 8]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Dong YH]] |
| - | [[Category: | + | [[Category: Gao ZQ]] |
| - | [[Category: | + | [[Category: Lan K]] |
| - | [[Category: | + | [[Category: Yuan F]] |
Current revision
Dimeric crystal structure of ORF57 from KSHV
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