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6fnk
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==Crystal Structure of Ephrin B4 (EphB4) Receptor Protein Kinase with a pyrazolo[3,4-d]pyrimidine fragment of NVP-BHG712== | ==Crystal Structure of Ephrin B4 (EphB4) Receptor Protein Kinase with a pyrazolo[3,4-d]pyrimidine fragment of NVP-BHG712== | ||
| - | <StructureSection load='6fnk' size='340' side='right' caption='[[6fnk]], [[Resolution|resolution]] 1.05Å' scene=''> | + | <StructureSection load='6fnk' size='340' side='right'caption='[[6fnk]], [[Resolution|resolution]] 1.05Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6fnk]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FNK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FNK FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6fnk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FNK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FNK FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DXK:1-methyl-6-pyridin-3-yl-pyrazolo[3,4-d]pyrimidin-4-amine'>DXK</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DXK:1-methyl-6-pyridin-3-yl-pyrazolo[3,4-d]pyrimidin-4-amine'>DXK</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">EPHB4, HTK, MYK1, TYRO11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fnk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fnk OCA], [http://pdbe.org/6fnk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fnk RCSB], [http://www.ebi.ac.uk/pdbsum/6fnk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fnk ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fnk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fnk OCA], [http://pdbe.org/6fnk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fnk RCSB], [http://www.ebi.ac.uk/pdbsum/6fnk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fnk ProSAT]</span></td></tr> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Receptor protein-tyrosine kinase]] | [[Category: Receptor protein-tyrosine kinase]] | ||
| - | [[Category: | + | [[Category: Kudlinzki, D]] |
| - | [[Category: | + | [[Category: Linhard, V L]] |
| - | [[Category: | + | [[Category: Saxena, K]] |
| - | [[Category: | + | [[Category: Schwalbe, H]] |
| - | [[Category: | + | [[Category: Troester, A]] |
| - | [[Category: | + | [[Category: Witt, K]] |
[[Category: Complex]] | [[Category: Complex]] | ||
[[Category: Inhibitor]] | [[Category: Inhibitor]] | ||
[[Category: Protein tyrosine kinase]] | [[Category: Protein tyrosine kinase]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Current revision
Crystal Structure of Ephrin B4 (EphB4) Receptor Protein Kinase with a pyrazolo[3,4-d]pyrimidine fragment of NVP-BHG712
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