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2otd

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[[Image:2otd.gif|left|200px]]
 
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{{Structure
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==The crystal structure of the glycerophosphodiester phosphodiesterase from Shigella flexneri 2a==
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|PDB= 2otd |SIZE=350|CAPTION= <scene name='initialview01'>2otd</scene>, resolution 2.60&Aring;
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<StructureSection load='2otd' size='340' side='right'caption='[[2otd]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>
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<table><tr><td colspan='2'>[[2otd]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/"shigella_paradysenteriae"_weldin_1927 "shigella paradysenteriae" weldin 1927]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OTD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OTD FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphodiesterase_I Phosphodiesterase I], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.4.1 3.1.4.1] </span>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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|GENE= ugpQ, SF3466, S_4296 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=623 Shigella flexneri])
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam03009 GDPD], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK09454 ugpQ]</span>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ugpQ, SF3466, S_4296 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=623 "Shigella paradysenteriae" Weldin 1927])</td></tr>
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|RELATEDENTRY=
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Phosphodiesterase_I Phosphodiesterase I], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.4.1 3.1.4.1] </span></td></tr>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2otd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2otd OCA], [http://www.ebi.ac.uk/pdbsum/2otd PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2otd RCSB]</span>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2otd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2otd OCA], [https://pdbe.org/2otd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2otd RCSB], [https://www.ebi.ac.uk/pdbsum/2otd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2otd ProSAT], [https://www.topsan.org/Proteins/MCSG/2otd TOPSAN]</span></td></tr>
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}}
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</table>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ot/2otd_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2otd ConSurf].
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<div style="clear:both"></div>
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'''The crystal structure of the glycerophosphodiester phosphodiesterase from Shigella flexneri 2a'''
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==See Also==
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*[[Phosphodiesterase 3D structures|Phosphodiesterase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2OTD is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Shigella_flexneri Shigella flexneri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OTD OCA].
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[[Category: Shigella paradysenteriae weldin 1927]]
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[[Category: Large Structures]]
[[Category: Phosphodiesterase I]]
[[Category: Phosphodiesterase I]]
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[[Category: Shigella flexneri]]
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[[Category: Clancy, S]]
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[[Category: Single protein]]
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[[Category: Jiang, S]]
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[[Category: Clancy, S.]]
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[[Category: Joachimiak, A]]
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[[Category: Jiang, S.]]
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[[Category: Structural genomic]]
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[[Category: Joachimiak, A.]]
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[[Category: Wu, R]]
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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[[Category: Zhang, R]]
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[[Category: Wu, R.]]
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[[Category: Glycerophosphodiester phosphodiesterase]]
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[[Category: Zhang, R.]]
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[[Category: Hydrolase]]
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[[Category: glycerophosphodiester phosphodiesterase]]
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[[Category: Mcsg]]
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[[Category: mcsg]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: midwest center for structural genomic]]
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[[Category: protein structure initiative]]
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[[Category: psi-2]]
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[[Category: structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:22:49 2008''
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Current revision

The crystal structure of the glycerophosphodiester phosphodiesterase from Shigella flexneri 2a

PDB ID 2otd

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