2lw4
From Proteopedia
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==Solution NMR Structure of Human Transcription Elongation Factor A protein 2, Central Domain, Northeast Structural Genomics Consortium (NESG) Target HR8682B== | ==Solution NMR Structure of Human Transcription Elongation Factor A protein 2, Central Domain, Northeast Structural Genomics Consortium (NESG) Target HR8682B== | ||
| - | <StructureSection load='2lw4' size='340' side='right' caption='[[2lw4 | + | <StructureSection load='2lw4' size='340' side='right'caption='[[2lw4]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2lw4]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2lw4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LW4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LW4 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lw4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lw4 OCA], [https://pdbe.org/2lw4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lw4 RCSB], [https://www.ebi.ac.uk/pdbsum/2lw4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lw4 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/TCEA2_HUMAN TCEA2_HUMAN] Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.<ref>PMID:12034815</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Acton | + | [[Category: Large Structures]] |
| - | [[Category: Eletsky | + | [[Category: Acton TB]] |
| - | [[Category: Everett | + | [[Category: Eletsky A]] |
| - | [[Category: Janjua | + | [[Category: Everett JK]] |
| - | [[Category: Kohan | + | [[Category: Janjua H]] |
| - | [[Category: Montelione | + | [[Category: Kohan E]] |
| - | + | [[Category: Montelione GT]] | |
| - | [[Category: Szyperski | + | [[Category: Szyperski T]] |
| - | [[Category: Wang | + | [[Category: Wang D]] |
| - | [[Category: Xiao | + | [[Category: Xiao R]] |
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Current revision
Solution NMR Structure of Human Transcription Elongation Factor A protein 2, Central Domain, Northeast Structural Genomics Consortium (NESG) Target HR8682B
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Categories: Homo sapiens | Large Structures | Acton TB | Eletsky A | Everett JK | Janjua H | Kohan E | Montelione GT | Szyperski T | Wang D | Xiao R
