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2m5d

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==Solution Structure of the Bacillus cereus Metallo-Beta-Lactamase BcII in Complex with R-Thiomandelic Acid==
==Solution Structure of the Bacillus cereus Metallo-Beta-Lactamase BcII in Complex with R-Thiomandelic Acid==
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<StructureSection load='2m5d' size='340' side='right' caption='[[2m5d]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2m5d' size='340' side='right'caption='[[2m5d]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2m5d]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_14579 Atcc 14579]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M5D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2M5D FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2m5d]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_cereus Bacillus cereus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M5D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M5D FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=RTD:(2R)-PHENYL(SULFANYL)ETHANOIC+ACID'>RTD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2m5c|2m5c]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=RTD:(2R)-PHENYL(SULFANYL)ETHANOIC+ACID'>RTD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">blm ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1396 ATCC 14579])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m5d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m5d OCA], [https://pdbe.org/2m5d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m5d RCSB], [https://www.ebi.ac.uk/pdbsum/2m5d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m5d ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2m5d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m5d OCA], [http://pdbe.org/2m5d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2m5d RCSB], [http://www.ebi.ac.uk/pdbsum/2m5d PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2m5d ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/BLA2_BACCE BLA2_BACCE]] Can hydrolyze carbapenem compounds.
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[https://www.uniprot.org/uniprot/BLA2_BACCE BLA2_BACCE] Can hydrolyze carbapenem compounds.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[Beta-lactamase|Beta-lactamase]]
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*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 14579]]
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[[Category: Bacillus cereus]]
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[[Category: Beta-lactamase]]
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[[Category: Large Structures]]
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[[Category: Damblon, C F]]
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[[Category: Damblon CF]]
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[[Category: Karsisiotis, A I]]
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[[Category: Karsisiotis AI]]
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[[Category: Roberts, G C.K]]
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[[Category: Roberts GCK]]
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[[Category: Bcii]]
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[[Category: Broad spectrum inhibitor]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Mercaptocarboxylate inhibitor]]
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[[Category: Metallo-beta-lactamase]]
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[[Category: R-thiomandelic acid]]
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Current revision

Solution Structure of the Bacillus cereus Metallo-Beta-Lactamase BcII in Complex with R-Thiomandelic Acid

PDB ID 2m5d

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