2lui
From Proteopedia
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==Structure of the PICK PDZ domain in complex with the DAT C-terminal== | ==Structure of the PICK PDZ domain in complex with the DAT C-terminal== | ||
| - | <StructureSection load='2lui' size='340' side='right' caption='[[2lui | + | <StructureSection load='2lui' size='340' side='right'caption='[[2lui]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2lui]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2lui]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LUI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LUI FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lui FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lui OCA], [https://pdbe.org/2lui PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lui RCSB], [https://www.ebi.ac.uk/pdbsum/2lui PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lui ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/PICK1_RAT PICK1_RAT] Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel.<ref>PMID:16138078</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Erlendsson | + | [[Category: Rattus norvegicus]] |
| - | [[Category: Gether | + | [[Category: Erlendsson S]] |
| - | [[Category: Heidarsson | + | [[Category: Gether U]] |
| - | [[Category: Madsen | + | [[Category: Heidarsson PO]] |
| - | [[Category: Poulsen | + | [[Category: Madsen KL]] |
| - | [[Category: Rathje | + | [[Category: Poulsen FM]] |
| - | [[Category: Teilum | + | [[Category: Rathje M]] |
| - | + | [[Category: Teilum K]] | |
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Current revision
Structure of the PICK PDZ domain in complex with the DAT C-terminal
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