6ed7
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of 7,8-diaminopelargonic acid synthase bound to inhibitor MAC13772== | |
| + | <StructureSection load='6ed7' size='340' side='right'caption='[[6ed7]], [[Resolution|resolution]] 2.43Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6ed7]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ED7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ED7 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.43Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=J4J:2-[(2-nitrophenyl)sulfanyl]acetohydrazide'>J4J</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ed7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ed7 OCA], [https://pdbe.org/6ed7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ed7 RCSB], [https://www.ebi.ac.uk/pdbsum/6ed7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ed7 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/BIOA_ECOLI BIOA_ECOLI] Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor.<ref>PMID:1092681</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Aminotransferase 3D structures|Aminotransferase 3D structures]] | |
| - | + | *[[7%2C8-diaminopelargonic acid synthase 3D structures|7%2C8-diaminopelargonic acid synthase 3D structures]] | |
| - | [[Category: | + | == References == |
| - | [[Category: | + | <references/> |
| - | [[Category: Brown | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Escherichia coli]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| + | [[Category: Brown CM]] | ||
| + | [[Category: Brown ED]] | ||
| + | [[Category: Chan J]] | ||
| + | [[Category: Junop MS]] | ||
| + | [[Category: Zlitni S]] | ||
Current revision
Crystal structure of 7,8-diaminopelargonic acid synthase bound to inhibitor MAC13772
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Categories: Escherichia coli | Large Structures | Brown CM | Brown ED | Chan J | Junop MS | Zlitni S
