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6hae

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'''Unreleased structure'''
 
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The entry 6hae is ON HOLD until Paper Publication
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==Crystal structure of [Fe]-hydrogenase (Hmd) from Methanococcus aeolicus in complex with FeGP cofactor and methenyl-tetrahydromethanopterin (close form B)==
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<StructureSection load='6hae' size='340' side='right'caption='[[6hae]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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Authors: Huang, G., Wagner, T., Wodrich, M.D., Ataka, K., Bill, E., Ermler, U., Hu, X., Shima, S.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6hae]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HAE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6HAE FirstGlance]. <br>
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Description: Crystal structure of [Fe]-hydrogenase (Hmd) from Methanococcus aeolicus in complex with FeGP cofactor and methenyl-tetrahydromethanopterin (close form B)
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2PE:NONAETHYLENE+GLYCOL'>2PE</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=E4M:1-{4-[(6S,6aR,7R)-3-amino-6,7-dimethyl-1-oxo-1,2,5,6,6a,7-hexahydro-8H-imidazo[1,5-f]pteridin-10-ium-8-yl]phenyl}-1-deoxy-5-O-{5-O-[(S)-{[(1S)-1,3-dicarboxypropyl]oxy}(hydroxy)phosphoryl]-alpha-D-ribofuranosyl}-D-ribitol'>E4M</scene>, <scene name='pdbligand=FE9:IRON-GUANYLYL+PYRIDINOL+COFACTOR'>FE9</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/5,10-methenyltetrahydromethanopterin_hydrogenase 5,10-methenyltetrahydromethanopterin hydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.12.98.2 1.12.98.2] </span></td></tr>
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[[Category: Shima, S]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6hae FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hae OCA], [http://pdbe.org/6hae PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6hae RCSB], [http://www.ebi.ac.uk/pdbsum/6hae PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6hae ProSAT]</span></td></tr>
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[[Category: Wagner, T]]
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/A6UVT1_META3 A6UVT1_META3]] Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.[HAMAP-Rule:MF_01090]
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__TOC__
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</StructureSection>
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[[Category: 5,10-methenyltetrahydromethanopterin hydrogenase]]
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[[Category: Large Structures]]
[[Category: Ataka, K]]
[[Category: Ataka, K]]
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[[Category: Bill, E]]
[[Category: Ermler, U]]
[[Category: Ermler, U]]
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[[Category: Bill, E]]
 
[[Category: Hu, X]]
[[Category: Hu, X]]
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[[Category: Wodrich, M.D]]
 
[[Category: Huang, G]]
[[Category: Huang, G]]
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[[Category: Shima, S]]
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[[Category: Wagner, T]]
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[[Category: Wodrich, M D]]
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[[Category: C1-metabolism]]
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[[Category: Catalytic cycle]]
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[[Category: Conformational rearrangement]]
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[[Category: Fe-guanylylpyridinol cofactor]]
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[[Category: Hydride-transfer]]
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[[Category: Methanogenesis]]
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[[Category: Oxidoreductase]]
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[[Category: Tetrahydromethanopterin]]

Current revision

Crystal structure of [Fe]-hydrogenase (Hmd) from Methanococcus aeolicus in complex with FeGP cofactor and methenyl-tetrahydromethanopterin (close form B)

PDB ID 6hae

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