6bwf

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==4.1 angstrom Mg2+-unbound structure of mouse TRPM7==
==4.1 angstrom Mg2+-unbound structure of mouse TRPM7==
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<StructureSection load='6bwf' size='340' side='right' caption='[[6bwf]], [[Resolution|resolution]] 4.10&Aring;' scene=''>
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<SX load='6bwf' size='340' side='right' viewer='molstar' caption='[[6bwf]], [[Resolution|resolution]] 4.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6bwf]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BWF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BWF FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6bwf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BWF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6BWF FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNK:UNKNOWN'>UNK</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.1&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bwf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bwf OCA], [http://pdbe.org/6bwf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bwf RCSB], [http://www.ebi.ac.uk/pdbsum/6bwf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bwf ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6bwf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bwf OCA], [https://pdbe.org/6bwf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6bwf RCSB], [https://www.ebi.ac.uk/pdbsum/6bwf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6bwf ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TRPM7_MOUSE TRPM7_MOUSE] Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium. Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1).<ref>PMID:11385574</ref>
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== References ==
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<references/>
__TOC__
__TOC__
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</StructureSection>
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</SX>
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[[Category: Abiria, S A]]
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[[Category: Large Structures]]
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[[Category: Clapham, D E]]
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[[Category: Mus musculus]]
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[[Category: Duan, J]]
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[[Category: Abiria SA]]
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[[Category: Li, Z]]
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[[Category: Clapham DE]]
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[[Category: Zhang, J]]
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[[Category: Duan J]]
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[[Category: Cryoem]]
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[[Category: Li Z]]
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[[Category: Membrane protein]]
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[[Category: Zhang J]]
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[[Category: Truncated mouse trpm7]]
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Current revision

4.1 angstrom Mg2+-unbound structure of mouse TRPM7

6bwf, resolution 4.10Å

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