6cza

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==The arsenate respiratory reductase (Arr) complex from Shewanella sp. ANA-3 bound to phosphate==
==The arsenate respiratory reductase (Arr) complex from Shewanella sp. ANA-3 bound to phosphate==
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<StructureSection load='6cza' size='340' side='right' caption='[[6cza]], [[Resolution|resolution]] 1.71&Aring;' scene=''>
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<StructureSection load='6cza' size='340' side='right'caption='[[6cza]], [[Resolution|resolution]] 1.71&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6cza]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CZA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CZA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6cza]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Shewanella_sp._ANA-3 Shewanella sp. ANA-3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CZA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6CZA FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=MGD:2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE+GUANOSINE+DINUCLEOTIDE'>MGD</scene>, <scene name='pdbligand=MO:MOLYBDENUM+ATOM'>MO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG5:1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE'>PG5</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.71&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[d_1000233067|d_1000233067]], [[d_1000233068|d_1000233068]], [[d_1000233069|d_1000233069]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=MGD:2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE+GUANOSINE+DINUCLEOTIDE'>MGD</scene>, <scene name='pdbligand=MO:MOLYBDENUM+ATOM'>MO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG5:1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE'>PG5</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6cza FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cza OCA], [http://pdbe.org/6cza PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cza RCSB], [http://www.ebi.ac.uk/pdbsum/6cza PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cza ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6cza FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cza OCA], [https://pdbe.org/6cza PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6cza RCSB], [https://www.ebi.ac.uk/pdbsum/6cza PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6cza ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ARRA_SHESA ARRA_SHESA] Component of the arsenate respiratory reductase (Arr) complex, which catalyzes the reduction of arsenate (As(V)) to arsenite (As(III)) (PubMed:12939408, PubMed:17951391, PubMed:30104376). ArrA is the arsenate-binding subunit (PubMed:30104376). The periplasmic localization of this complex may allow the cell to couple arsenate reduction to energy production before arsenate can be transported to the cell cytoplasm and enter the ars detoxification pathway, an energy-requiring process (PubMed:17951391).<ref>PMID:12939408</ref> <ref>PMID:17951391</ref> <ref>PMID:30104376</ref>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Glasser, N R]]
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[[Category: Large Structures]]
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[[Category: Newman, D K]]
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[[Category: Shewanella sp. ANA-3]]
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[[Category: Arsenate]]
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[[Category: Glasser NR]]
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[[Category: Molybdoprotein]]
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[[Category: Newman DK]]
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[[Category: Molybdopterin]]
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[[Category: Oxidoreductase]]
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[[Category: Phosphate]]
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Current revision

The arsenate respiratory reductase (Arr) complex from Shewanella sp. ANA-3 bound to phosphate

PDB ID 6cza

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