2nzj
From Proteopedia
(Difference between revisions)
(One intermediate revision not shown.) | |||
Line 1: | Line 1: | ||
==The crystal structure of REM1 in complex with GDP== | ==The crystal structure of REM1 in complex with GDP== | ||
- | <StructureSection load='2nzj' size='340' side='right' caption='[[2nzj]], [[Resolution|resolution]] 2.50Å' scene=''> | + | <StructureSection load='2nzj' size='340' side='right'caption='[[2nzj]], [[Resolution|resolution]] 2.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[2nzj]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2nzj]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NZJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NZJ FirstGlance]. <br> |
- | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nzj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nzj OCA], [https://pdbe.org/2nzj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nzj RCSB], [https://www.ebi.ac.uk/pdbsum/2nzj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nzj ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
- | [ | + | [https://www.uniprot.org/uniprot/REM1_HUMAN REM1_HUMAN] Promotes endothelial cell sprouting and actin cytoskeletal reorganization. May be involved in angiogenesis. May function in Ca(2+) signaling. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Line 22: | Line 22: | ||
==See Also== | ==See Also== | ||
- | *[[GTP-binding protein|GTP-binding protein]] | + | *[[GTP-binding protein 3D structures|GTP-binding protein 3D structures]] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: | + | [[Category: Homo sapiens]] |
- | [[Category: Arrowsmith | + | [[Category: Large Structures]] |
- | [[Category: Berridge | + | [[Category: Arrowsmith CH]] |
- | [[Category: Bray | + | [[Category: Berridge G]] |
- | [[Category: Burgess | + | [[Category: Bray J]] |
- | + | [[Category: Burgess N]] | |
- | [[Category: Doyle | + | [[Category: Doyle D]] |
- | [[Category: Edwards | + | [[Category: Edwards A]] |
- | [[Category: Elkins | + | [[Category: Elkins JM]] |
- | [[Category: Gileadi | + | [[Category: Gileadi O]] |
- | [[Category: Gorrec | + | [[Category: Gorrec F]] |
- | [[Category: Johansson | + | [[Category: Johansson C]] |
- | [[Category: Marsden | + | [[Category: Marsden B]] |
- | [[Category: Papagrigoriou | + | [[Category: Papagrigoriou E]] |
- | + | [[Category: Salah E]] | |
- | [[Category: Salah | + | [[Category: Soundararajan M]] |
- | [[Category: Soundararajan | + | [[Category: Sundstrom M]] |
- | [[Category: Sundstrom | + | [[Category: Turnbull AP]] |
- | [[Category: Turnbull | + | [[Category: Ugochukwu E]] |
- | [[Category: Ugochukwu | + | [[Category: Umeano C]] |
- | [[Category: Umeano | + | [[Category: Watts S]] |
- | [[Category: Watts | + | [[Category: Weigelt J]] |
- | [[Category: Weigelt | + | [[Category: Yang X]] |
- | [[Category: Yang | + | [[Category: Von Delft F]] |
- | [[Category: | + | |
- | + | ||
- | + | ||
- | + | ||
- | + | ||
- | + |
Current revision
The crystal structure of REM1 in complex with GDP
|
Categories: Homo sapiens | Large Structures | Arrowsmith CH | Berridge G | Bray J | Burgess N | Doyle D | Edwards A | Elkins JM | Gileadi O | Gorrec F | Johansson C | Marsden B | Papagrigoriou E | Salah E | Soundararajan M | Sundstrom M | Turnbull AP | Ugochukwu E | Umeano C | Watts S | Weigelt J | Yang X | Von Delft F