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2nzd

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==Nucleosome core particle containing 145 bp of DNA==
==Nucleosome core particle containing 145 bp of DNA==
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<StructureSection load='2nzd' size='340' side='right' caption='[[2nzd]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
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<StructureSection load='2nzd' size='340' side='right'caption='[[2nzd]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2nzd]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/African_clawed_frog African clawed frog]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NZD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2NZD FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2nzd]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NZD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NZD FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1kx5|1kx5]], [[1kx3|1kx3]], [[1kx4|1kx4]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2nzd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nzd OCA], [http://pdbe.org/2nzd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2nzd RCSB], [http://www.ebi.ac.uk/pdbsum/2nzd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2nzd ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nzd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nzd OCA], [https://pdbe.org/2nzd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nzd RCSB], [https://www.ebi.ac.uk/pdbsum/2nzd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nzd ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/H2B11_XENLA H2B11_XENLA]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [[http://www.uniprot.org/uniprot/H4_XENLA H4_XENLA]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
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[https://www.uniprot.org/uniprot/H32_XENLA H32_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
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*[[Histone|Histone]]
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*[[Histone 3D structures|Histone 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: African clawed frog]]
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[[Category: Large Structures]]
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[[Category: Davey, C A]]
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[[Category: Xenopus laevis]]
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[[Category: Ong, M S]]
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[[Category: Davey CA]]
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[[Category: Richmond, T J]]
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[[Category: Ong MS]]
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[[Category: Chromatin]]
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[[Category: Richmond TJ]]
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[[Category: Dna kinking]]
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[[Category: Dna stretching]]
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[[Category: Double-helix]]
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[[Category: Histone]]
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[[Category: Nucleosome]]
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[[Category: Structural protein-dna complex]]
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Current revision

Nucleosome core particle containing 145 bp of DNA

PDB ID 2nzd

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