5qiz
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Covalent fragment group deposition -- Crystal Structure of OUTB2 in complex with PCM-0103080== | |
| + | <StructureSection load='5qiz' size='340' side='right'caption='[[5qiz]], [[Resolution|resolution]] 1.63Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5qiz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QIZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QIZ FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.63Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=J64:N-[(5-chlorothiophen-2-yl)methyl]acetamide'>J64</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qiz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qiz OCA], [https://pdbe.org/5qiz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qiz RCSB], [https://www.ebi.ac.uk/pdbsum/5qiz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qiz ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/OTUB2_HUMAN OTUB2_HUMAN] Hydrolase that can remove conjugated ubiquitin from proteins in vitro and may therefore play an important regulatory role at the level of protein turnover by preventing degradation. Mediates deubiquitination of both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains, with a preference for 'Lys-63'-linked polyubiquitin chains.<ref>PMID:12704427</ref> <ref>PMID:18954305</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Thioesterase 3D structures|Thioesterase 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Brandao-Neto | + | [[Category: Arrowsmith CH]] |
| - | [[Category: | + | [[Category: Bountra C]] |
| - | [[Category: Douangamath | + | [[Category: Bradley AR]] |
| - | [[Category: Krojer | + | [[Category: Brandao-Neto J]] |
| - | [[Category: | + | [[Category: Collins P]] |
| - | [[Category: | + | [[Category: Douangamath A]] |
| - | [[Category: Sethi | + | [[Category: Edwards A]] |
| - | [[Category: | + | [[Category: Krojer T]] |
| - | [[Category: | + | [[Category: London N]] |
| + | [[Category: Resnick E]] | ||
| + | [[Category: Sethi R]] | ||
| + | [[Category: Talon R]] | ||
| + | [[Category: Von Delft F]] | ||
Current revision
Covalent fragment group deposition -- Crystal Structure of OUTB2 in complex with PCM-0103080
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bountra C | Bradley AR | Brandao-Neto J | Collins P | Douangamath A | Edwards A | Krojer T | London N | Resnick E | Sethi R | Talon R | Von Delft F
