6bx3
From Proteopedia
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- | '''Unreleased structure''' | ||
- | + | ==Structure of histone H3k4 methyltransferase== | |
- | + | <SX load='6bx3' size='340' side='right' viewer='molstar' caption='[[6bx3]], [[Resolution|resolution]] 4.30Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[6bx3]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C] and [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_YJM789 Saccharomyces cerevisiae YJM789]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BX3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6BX3 FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.3Å</td></tr> | |
- | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6bx3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bx3 OCA], [https://pdbe.org/6bx3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6bx3 RCSB], [https://www.ebi.ac.uk/pdbsum/6bx3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6bx3 ProSAT]</span></td></tr> |
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/SPP1_YEAST SPP1_YEAST] The COMPASS (Set1C) complex specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.<ref>PMID:11742990</ref> <ref>PMID:11805083</ref> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </SX> | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Saccharomyces cerevisiae S288C]] | ||
+ | [[Category: Saccharomyces cerevisiae YJM789]] | ||
+ | [[Category: Qu QH]] | ||
+ | [[Category: Skiniotis G]] |
Current revision
Structure of histone H3k4 methyltransferase
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