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| - | [[Image:2p5a.jpg|left|200px]] | + | #REDIRECT [[3hvc]] This PDB entry is obsolete and replaced by 3hvc |
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| - | {{Structure
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| - | |PDB= 2p5a |SIZE=350|CAPTION= <scene name='initialview01'>2p5a</scene>, resolution 2.10Å
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| - | |SITE= <scene name='pdbsite=AC1:Gg5+Binding+Site+For+Residue+A+361'>AC1</scene> and <scene name='pdbsite=AC2:Gg5+Binding+Site+For+Residue+A+362'>AC2</scene>
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| - | |LIGAND= <scene name='pdbligand=GG5:4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINE'>GG5</scene>
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| - | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Mitogen-activated_protein_kinase Mitogen-activated protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.24 2.7.11.24] </span>
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| - | |GENE= MAPK14, CSBP, CSBP1, CSBP2, MXI2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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| - | |DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00180 S_TKc], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=smart00220 S_TKc]</span>
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| - | |RELATEDENTRY=
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| - | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2p5a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p5a OCA], [http://www.ebi.ac.uk/pdbsum/2p5a PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2p5a RCSB]</span>
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| - | }}
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| - | '''Second binding site for a p38a kinase inhibitor'''
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| - | ==About this Structure==
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| - | 2P5A is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P5A OCA].
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| - | [[Category: Homo sapiens]]
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| - | [[Category: Mitogen-activated protein kinase]]
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| - | [[Category: Single protein]]
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| - | [[Category: Perry, J J.]]
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| - | [[Category: Tainer, J A.]]
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| - | [[Category: isoform-2]]
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| - | [[Category: map kinase]]
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| - | [[Category: p38]]
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| - | [[Category: serine/threonine-protein kinase]]
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| - | [[Category: transferase]]
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:29:56 2008''
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