|
|
| (3 intermediate revisions not shown.) |
| Line 1: |
Line 1: |
| - | [[Image:2p8k.jpg|left|200px]] | + | #REDIRECT [[3h4v]] This PDB entry is obsolete and replaced by 3h4v |
| - | | + | |
| - | {{Structure
| + | |
| - | |PDB= 2p8k |SIZE=350|CAPTION= <scene name='initialview01'>2p8k</scene>, resolution 2.40Å
| + | |
| - | |SITE=
| + | |
| - | |LIGAND= <scene name='pdbligand=DYP:1-[1-(4-{[(2,4-DIAMINOPTERIDIN-6-YL)METHYL]AMINO}BENZYL)PIPERIDIN-4-YL]PROPAN-1-ONE'>DYP</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>
| + | |
| - | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Pteridine_reductase Pteridine reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.33 1.5.1.33] </span>
| + | |
| - | |GENE= PTR1, HMTXR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5664 Leishmania major])
| + | |
| - | |DOMAIN=
| + | |
| - | |RELATEDENTRY=
| + | |
| - | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2p8k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p8k OCA], [http://www.ebi.ac.uk/pdbsum/2p8k PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2p8k RCSB]</span>
| + | |
| - | }}
| + | |
| - | | + | |
| - | '''Selective screening and design to identify inhibitors of Leishmania major pteridine reductase 1.'''
| + | |
| - | | + | |
| - | | + | |
| - | ==About this Structure==
| + | |
| - | 2P8K is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Leishmania_major Leishmania major]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P8K OCA].
| + | |
| - | [[Category: Leishmania major]]
| + | |
| - | [[Category: Pteridine reductase]]
| + | |
| - | [[Category: Single protein]]
| + | |
| - | [[Category: Gibellini, F.]]
| + | |
| - | [[Category: Hunter, W N.]]
| + | |
| - | [[Category: Mcluskey, K.]]
| + | |
| - | [[Category: inhibitor]]
| + | |
| - | [[Category: leishmania]]
| + | |
| - | [[Category: oxidoreductase]]
| + | |
| - | [[Category: ptr1]]
| + | |
| - | [[Category: short-chain reductase]]
| + | |
| - | [[Category: trypanosoma]]
| + | |
| - | | + | |
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:32:10 2008''
| + | |
