6m8o

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m (Protected "6m8o" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 6m8o is ON HOLD
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==Crystal structure of the receiver domain of LytR from Staphylococcus aureus==
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<StructureSection load='6m8o' size='340' side='right'caption='[[6m8o]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6m8o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6M8O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6M8O FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6m8o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6m8o OCA], [https://pdbe.org/6m8o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6m8o RCSB], [https://www.ebi.ac.uk/pdbsum/6m8o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6m8o ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LYTR_STAA8 LYTR_STAA8] Member of the two-component regulatory system LytR/LytS that regulates genes involved in autolysis, programmed cell death, biofilm formation and cell wall metabolism (PubMed:19502411). Participates also in sensing and responding to host defense cationic antimicrobial peptides (HDPs) (PubMed:23733465). Upon phosphorylation by LytS, functions as a transcription regulator by direct binding to promoter regions of target genes including lrgA and lrgB, to positively regulate their expression (PubMed:8824633, PubMed:25491472).<ref>PMID:19502411</ref> <ref>PMID:23733465</ref> <ref>PMID:25491472</ref> <ref>PMID:8824633</ref>
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Authors: Shala-Lawrence, A., Audette, G.F.
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==See Also==
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*[[Response regulator 3D structure|Response regulator 3D structure]]
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Description: Crystal structure of the receiver domain of LytR from Staphylococcus aureus
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== References ==
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[[Category: Unreleased Structures]]
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<references/>
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[[Category: Audette, G.F]]
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__TOC__
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[[Category: Shala-Lawrence, A]]
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Staphylococcus aureus]]
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[[Category: Audette GF]]
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[[Category: Shala-Lawrence A]]

Current revision

Crystal structure of the receiver domain of LytR from Staphylococcus aureus

PDB ID 6m8o

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