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4zcs

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==Crystal structure of the C-terminal catalytic domain of Plasmodium falciparum CTP:phosphocholine cytidylyltransferase in complex with CDP-choline==
==Crystal structure of the C-terminal catalytic domain of Plasmodium falciparum CTP:phosphocholine cytidylyltransferase in complex with CDP-choline==
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<StructureSection load='4zcs' size='340' side='right' caption='[[4zcs]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
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<StructureSection load='4zcs' size='340' side='right'caption='[[4zcs]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4zcs]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Plaf7 Plaf7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZCS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZCS FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4zcs]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZCS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZCS FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CDC:[2-CYTIDYLATE-O-PHOSPHONYLOXYL]-ETHYL-TRIMETHYL-AMMONIUM'>CDC</scene>, <scene name='pdbligand=P33:3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL'>P33</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4zcp|4zcp]], [[4zcq|4zcq]], [[4zcr|4zcr]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CDC:[2-CYTIDYLATE-O-PHOSPHONYLOXYL]-ETHYL-TRIMETHYL-AMMONIUM'>CDC</scene>, <scene name='pdbligand=P33:3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL'>P33</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PF3D7_1316600 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=36329 PLAF7])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4zcs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zcs OCA], [https://pdbe.org/4zcs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4zcs RCSB], [https://www.ebi.ac.uk/pdbsum/4zcs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4zcs ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Choline-phosphate_cytidylyltransferase Choline-phosphate cytidylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.15 2.7.7.15] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zcs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zcs OCA], [http://pdbe.org/4zcs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zcs RCSB], [http://www.ebi.ac.uk/pdbsum/4zcs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4zcs ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q8IEE9_PLAF7 Q8IEE9_PLAF7]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Choline-phosphate cytidylyltransferase]]
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[[Category: Large Structures]]
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[[Category: Plaf7]]
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[[Category: Plasmodium falciparum 3D7]]
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[[Category: Cerdan, R]]
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[[Category: Cerdan R]]
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[[Category: Guca, E]]
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[[Category: Guca E]]
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[[Category: Guichou, J F]]
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[[Category: Guichou J-F]]
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[[Category: Hoh, F]]
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[[Category: Hoh F]]
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[[Category: Cytidylyltransferase]]
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[[Category: Enzyme]]
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[[Category: Malaria]]
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[[Category: Phosphatidylcholine]]
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[[Category: Transferase]]
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Current revision

Crystal structure of the C-terminal catalytic domain of Plasmodium falciparum CTP:phosphocholine cytidylyltransferase in complex with CDP-choline

PDB ID 4zcs

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