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2pr2

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==Structure of Mycobacterium tuberculosis enoyl-ACP reductase with bound INH-NADP.==
==Structure of Mycobacterium tuberculosis enoyl-ACP reductase with bound INH-NADP.==
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<StructureSection load='2pr2' size='340' side='right' caption='[[2pr2]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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<StructureSection load='2pr2' size='340' side='right'caption='[[2pr2]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2pr2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PR2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PR2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2pr2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PR2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PR2 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DG1:(4S)-ISONICOTINIC-ACETYL-NICOTINAMIDE-ADENINE+DINUCLEOTIDE'>DG1</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">inhA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DG1:(4S)-ISONICOTINIC-ACETYL-NICOTINAMIDE-ADENINE+DINUCLEOTIDE'>DG1</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pr2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pr2 OCA], [https://pdbe.org/2pr2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pr2 RCSB], [https://www.ebi.ac.uk/pdbsum/2pr2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pr2 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pr2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pr2 OCA], [http://pdbe.org/2pr2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pr2 RCSB], [http://www.ebi.ac.uk/pdbsum/2pr2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2pr2 ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/INHA_MYCTU INHA_MYCTU]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
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*[[Enoyl-Acyl-Carrier Protein Reductase|Enoyl-Acyl-Carrier Protein Reductase]]
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*[[Enoyl-Acyl-Carrier Protein Reductase 3D structures|Enoyl-Acyl-Carrier Protein Reductase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Myctu]]
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[[Category: Large Structures]]
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[[Category: Argyrou, A]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Blanchard, J S]]
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[[Category: Argyrou A]]
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[[Category: Vetting, M W]]
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[[Category: Blanchard JS]]
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[[Category: Drug target of isoniazid]]
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[[Category: Vetting MW]]
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[[Category: Oxidoreductase]]
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Current revision

Structure of Mycobacterium tuberculosis enoyl-ACP reductase with bound INH-NADP.

PDB ID 2pr2

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