6cxo

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==Complement component-9==
==Complement component-9==
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<StructureSection load='6cxo' size='340' side='right' caption='[[6cxo]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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<StructureSection load='6cxo' size='340' side='right'caption='[[6cxo]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6cxo]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CXO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CXO FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6cxo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CXO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6CXO FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6cxo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cxo OCA], [http://pdbe.org/6cxo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cxo RCSB], [http://www.ebi.ac.uk/pdbsum/6cxo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cxo ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6cxo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cxo OCA], [https://pdbe.org/6cxo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6cxo RCSB], [https://www.ebi.ac.uk/pdbsum/6cxo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6cxo ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CO9_MOUSE CO9_MOUSE]] Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC.[UniProtKB:P02748]
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[https://www.uniprot.org/uniprot/CO9_MOUSE CO9_MOUSE] Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC.[UniProtKB:P02748]
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<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Caradoc-Davies, T T]]
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[[Category: Large Structures]]
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[[Category: Law, R H.P]]
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[[Category: Mus musculus]]
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[[Category: Spicer, B A]]
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[[Category: Caradoc-Davies TT]]
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[[Category: Complement]]
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[[Category: Law RHP]]
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[[Category: Complex]]
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[[Category: Spicer BA]]
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[[Category: Immune system]]
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[[Category: Immunity]]
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[[Category: Macpf]]
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Current revision

Complement component-9

PDB ID 6cxo

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